Typical dose

200-400 mg of elemental magnesium daily, typical...

Oral Oral safety: very low

About this supplement

Magnesium glycinate (also known as magnesium bisglycinate) is a chelated form of magnesium where magnesium is bound to two glycine molecules. This chelation enhances bioavailability and absorption in the gastrointestinal tract compared to inorganic magnesium salts. Glycine is a non-essential amino acid that serves as a calming neurotransmitter and may contribute additional benefits. This form is particularly valued for its high elemental magnesium content (approximately 14-16%), excellent tolerability with minimal laxative effect, and efficient cellular uptake. It is widely used in dietary supplements to address magnesium deficiency and support neurological, muscular, and metabolic functions.

How much to take

Typical amount
200-400 mg of elemental magnesium daily, typically divided into 2-3 doses.
Suggested range
100-500 mg elemental magnesium daily

Potential benefits

Benefits linked to this supplement form:

Things to watch for

Possible side effects linked to this form:

Health goals

Needs and goals this form may help with:

Other forms of Magnesium

Compare absorption and active amounts with sibling forms:

Technical details â–¼

Chemical ID (CAS)

14783-68-7

Formula

C4H8MgN2O4

Physical properties

Typically a fine, white to off-white crystalline powder. Soluble in water. Odorless. Stable under normal storage conditions.

How it’s made

Produced synthetically via a chelation reaction where magnesium oxide or magnesium hydroxide is reacted with glycine under controlled conditions. The process involves heating and pH adjustment to form the stable magnesium bisglycinate complex.