About Saccharomyces

Saccharomyces boulardii CNCM I-745 is a specific, well-researched strain of probiotic yeast originally isolated from lychee and mangosteen fruit in Southeast Asia. It is a non-pathogenic, thermophilic yeast that survives gastric acidity and transiently colonizes the gastrointestinal tract without permanently altering the gut microbiota. This strain is distinct from brewer's or baker's yeast (Saccharomyces cerevisiae) and is clinically documented for its ability to support gastrointestinal health, particularly in managing various forms of diarrhea and maintaining gut barrier function. The designation 'CNCM I-745' indicates it is deposited in the French National Collection of Microorganism Cultures (Collection Nationale de Cultures de Microorganismes).

Official resources

Fact sheets from the NIH Office of Dietary Supplements related to this ingredient group.

Dietary Supplement Label Database

Ingredient group data in NutriNav is aligned with the NIH Dietary Supplement Label Database (DSLD).

DSLD group id
1254

Compare All Forms

16 forms

Compare supplement forms of Saccharomyces by absorption quality and what your body actually gets from each:

High Moderate Low
Form Absorption Steps to absorb Notes Action
Lyophilized (freeze-dried) S. boulardii

Probiotic yeast; supports digestive health; helps maintain g...

  • Label category: natural
β€” β€” β€” View β†’
Saccharomyces β€” β€” β€” View β†’
Saccharomyces (unspecified)
  • DSLD group id: 2741
β€” β€” β€” View β†’
Saccharomyces boulardii β€” β€” β€” View β†’
Saccharomyces boulardii β€” β€” β€” View β†’
Saccharomyces boulardii CNCM I-745

A well-studied probiotic yeast strain for digestive support.

  • UNII: 9G5L16G8JZ
  • Label category: natural
β€” β€” β€” View β†’
Saccharomyces boulardii DBVPG 6763

Probiotic yeast for digestive support. Use during antibiotic...

  • Label category: natural
β€” β€” β€” View β†’
Saccharomyces boulardii lyo β€” β€” β€” View β†’
Saccharomyces boullardii β€” β€” β€” View β†’
Saccharomyces cerevisae β€” β€” β€” View β†’
Saccharomyces cerevisiae β€” β€” β€” View β†’
Saccharomyces cerevisiae β€” β€” β€” View β†’
Saccharomyces cerevisiae peptides β€” β€” β€” View β†’
Saccharomyces exiguus β€” β€” β€” View β†’
Saccharomyces turicensis β€” β€” β€” View β†’
Saccharomyces unisporus β€” β€” β€” View β†’

Also appears on labels as

Additional names seen on supplement labels for forms of this ingredient (beyond the main aliases above).

Boulardii, Brewer's yeast (probiotic strain), Freeze-dried Saccharomyces boulardii, Probiotic yeast, saccharomyces, Saccharomyces (unspecified), Saccharomyces boulardii CNCM I-745, Saccharomyces boulardii CNCM I-745 (related strain), saccharomyces sp. extract

Type: Other

Miscellaneous ingredients including fillers, binders, preservatives, artificial colors, flavors, sweeteners, and other additives found in supplements.

Absorption: Many of these ingredients are inert fillers or additives that may affect absorption of active ingredients.

Interactions: Some additives may have health concerns. Fillers may reduce absorption of other nutrients. Preservatives and artificial colors may cause adverse reactions in sensitive individuals.

Potential Benefits

Benefits associated with Saccharomyces forms:

And 11 more benefits...

Potential Side Effects

Side effects associated with Saccharomyces forms:

And 5 more side effects...