Part of
Saccharomyces
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Typical dose
Typically 250-500 mg (providing 1-10 billion CFU...
About this supplement
Lyophilized (freeze-dried) Saccharomyces boulardii is a non-pathogenic, thermophilic yeast strain used as a probiotic. The lyophilization process involves freezing the live yeast cells and removing water via sublimation under vacuum, resulting in a stable powder with enhanced shelf life and viability. This form preserves the metabolic activity and probiotic properties of S. boulardii, allowing it to survive gastric acidity and colonize the intestinal tract temporarily. It is widely used to support gastrointestinal health, particularly during antibiotic therapy, and to manage various forms of diarrhea.
How much to take
- Typical amount
- Typically 250-500 mg (providing 1-10 billion CFU) taken 1-2 times daily, often during meals. For antibiotic-associated diarrhea prevention, often taken twice daily during antibiotic course and for several days after.
- Suggested range
- 250-1000 mg daily (providing 1-20 billion CFU daily)
Potential benefits
Benefits linked to this supplement form:
Prevention of Antibiotic-Associated Diarrhea
Research strength: Very strong
Treatment of Acute Infectious DiarrheaResearch strength: Strong
Gut Barrier Function SupportResearch strength: Strong
Prevention of Traveler's DiarrheaResearch strength: Strong
Support in Inflammatory Bowel Disease (IBD)Research strength: Moderate
Things to watch for
Possible side effects linked to this form:
Health goals
Needs and goals this form may help with:
Other forms of Saccharomyces
Compare absorption and active amounts with sibling forms:
Saccharomyces
Saccharomyces (unspecified)
Saccharomyces boulardii
Saccharomyces boulardii
Saccharomyces boulardii CNCM I-745
A well-studied probiotic yeast strain for digestive support.
Saccharomyces boulardii DBVPG 6763
Probiotic yeast for digestive support. Use during antibiotic therapy. Not for im...
Saccharomyces boulardii lyo
Saccharomyces boullardii
Saccharomyces cerevisae
Saccharomyces cerevisiae
Saccharomyces cerevisiae
Saccharomyces cerevisiae peptides
Saccharomyces exiguus
Saccharomyces turicensis
Saccharomyces unisporus
Technical details â–¼
Physical properties
Fine, off-white to tan powder. Hygroscopic. Soluble or dispersible in water. Viable cell count typically ranges from 1 billion to 50 billion CFU/g. Lyophilized form is stable at room temperature for extended periods when protected from moisture.
How it’s made
Produced by fermentation of S. boulardii in a controlled bioreactor using a nutrient medium. The yeast biomass is harvested, washed, concentrated, and mixed with cryoprotectants (e.g., maltodextrin, sucrose). The slurry is frozen and then subjected to lyophilization (freeze-drying) under vacuum to remove water via sublimation, preserving cell viability. The resulting powder is then blended, standardized for colony-forming units (CFU), and packaged.