Typical dose
Typical supplemental doses range from 5 grams to...
Oral
Oral safety: very low
About this supplement
Free-form L-Glutamine Powder is a purified, crystalline form of the conditionally essential amino acid L-glutamine. It is the most abundant free amino acid in human blood and muscle tissue, serving as a critical nitrogen and carbon donor for numerous metabolic processes. In this free-form powder, L-glutamine is not bound to other amino acids in a peptide chain, allowing for rapid absorption and utilization by the body. It plays vital roles in protein synthesis, immune function, intestinal health, and cellular energy production, particularly for rapidly dividing cells like enterocytes and lymphocytes. The powder form is typically unflavored and highly soluble, designed for oral supplementation.
How much to take
- Typical amount
- Typical supplemental doses range from 5 grams to 30 grams per day, often divided into multiple doses. Doses for specific clinical conditions (e.g., supporting gut barrier function) can be higher, as directed by a healthcare provider.
- Suggested range
- 5-30 g daily
Potential benefits
Benefits linked to this supplement form:
Things to watch for
Possible side effects linked to this form:
Health goals
Needs and goals this form may help with:
Other forms of L-Glutamine
Compare absorption and active amounts with sibling forms:
Technical details â–¼
Chemical ID (CAS)
56-85-9
Formula
C5H10N2O3
Physical properties
White, crystalline powder. Odorless. Freely soluble in water, practically insoluble in ethanol and most organic solvents. Stable under dry, cool conditions.
How it’s made
Primarily produced via microbial fermentation using genetically modified bacteria (e.g., Corynebacterium glutamicum, Escherichia coli) that overproduce L-glutamine. The glutamine is then purified from the fermentation broth through processes including filtration, ion exchange, crystallization, and drying to produce a high-purity pharmaceutical/food-grade powder.