About Glucosamine

Glucosamine sulfate is a stabilized salt form of glucosamine, an amino sugar naturally produced in the human body and a key building block for glycosaminoglycans (GAGs) in cartilage. The sulfate form is commonly used in dietary supplements, particularly for joint health. The 'stabilized with NaCl or KCl' specification indicates that the glucosamine sulfate molecule is complexed with sodium chloride (NaCl) or potassium chloride (KCl) to prevent degradation and improve shelf stability. This is the form used in many clinical trials. It is distinct from glucosamine hydrochloride or N-acetyl glucosamine.

Dietary Supplement Label Database

Ingredient group data in NutriNav is aligned with the NIH Dietary Supplement Label Database (DSLD).

DSLD group id
7341

Compare All Forms

11 forms

Compare supplement forms of Glucosamine by absorption quality and what your body actually gets from each:

High Moderate Low
Form Absorption Steps to absorb Notes Action
Glucosamine (mixed type)
  • DSLD group id: 7341
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Glucosamine (mixed)
  • DSLD group id: 7342
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Glucosamine (unspecified)
  • DSLD group id: 7343
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Glucosamine 5-Methyltetrahydrofolate β€” β€” β€” View β†’
Glucosamine Hydrochloride β€” β€” β€” View β†’
Glucosamine Hydrochloride β€” β€” β€” View β†’
Glucosamine Hydrochloride (HCl)

Commonly used for joint support and osteoarthritis; typicall...

  • UNII: N08U5BOQ1K
  • CAS: 66-84-2 (for glucosamine base); 66-84-2 is often cited for hydrochloride form though technically refers to base
  • Label category: synthetic
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Glucosamine potassium sulfate β€” β€” β€” View β†’
Glucosamine Sulfate β€” β€” β€” View β†’
Glucosamine Sulfate (stabilized with NaCl or KCl)

Commonly used for joint comfort and osteoarthritis support....

  • UNII: C3H4N2O2Β·H2SO4Β·2NaCl (specific UNII not confidently assigned without lookup)
  • CAS: 29031-19-4 (glucosamine sulfate), 14999-43-0 (glucosamine sulfate potassium chloride), 38899-05-7 (glucosamine sulfate sodium chloride)
  • Label category: hybrid
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N-Acetylglucosamine (NAG)

Often combined with chondroitin for joint support; also used...

  • UNII: V956696549
  • CAS: 7512-17-6
  • Label category: synthetic
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Also appears on labels as

Additional names seen on supplement labels for forms of this ingredient (beyond the main aliases above).

2-Acetamido-2-deoxy-D-glucopyranose, 2-Amino-2-deoxy-D-glucopyranose hydrochloride, Chitosamine hydrochloride, Chitosamine sulfate, GlcNAc, gluc. hcl/sulfate 2kcl, Glucosamine (mixed), Glucosamine (mixed type), N-Acetyl-D-glucosamine, NAG

Type: Other

Miscellaneous ingredients including fillers, binders, preservatives, artificial colors, flavors, sweeteners, and other additives found in supplements.

Absorption: Many of these ingredients are inert fillers or additives that may affect absorption of active ingredients.

Interactions: Some additives may have health concerns. Fillers may reduce absorption of other nutrients. Preservatives and artificial colors may cause adverse reactions in sensitive individuals.

Potential Benefits

Benefits associated with Glucosamine forms:

And 5 more benefits...

Potential Side Effects

Side effects associated with Glucosamine forms:

And 5 more side effects...