Typical dose

Typically 1500 mg per day, taken as a single dos...

About this supplement

Glucosamine sulfate is a stabilized salt form of glucosamine, an amino sugar naturally produced in the human body and a key building block for glycosaminoglycans (GAGs) in cartilage. The sulfate form is commonly used in dietary supplements, particularly for joint health. The 'stabilized with NaCl or KCl' specification indicates that the glucosamine sulfate molecule is complexed with sodium chloride (NaCl) or potassium chloride (KCl) to prevent degradation and improve shelf stability. This is the form used in many clinical trials. It is distinct from glucosamine hydrochloride or N-acetyl glucosamine.

How much to take

Typical amount
Typically 1500 mg per day, taken as a single dose or divided into three 500 mg doses.
Suggested range
1000-1500 mg daily

Potential benefits

Benefits linked to this supplement form:

Things to watch for

Possible side effects linked to this form:

Health goals

Needs and goals this form may help with:

Other forms of Glucosamine

Compare absorption and active amounts with sibling forms:

Technical details â–¼

Chemical ID (CAS)

29031-19-4 (glucosamine sulfate), 14999-43-0 (glucosamine sulfate potassium chloride), 38899-05-7 (glucosamine sulfate sodium chloride)

Formula

C6H13NO5 · H2SO4 · 2NaCl (or 2KCl) - Variable based on stabilizer

Physical properties

Typically a fine, white to off-white crystalline powder. Hygroscopic. Soluble in water. The salt stabilization improves its stability compared to pure glucosamine sulfate, which is prone to degradation.

How it’s made

Primarily produced synthetically via hydrolysis and chemical modification of chitin from shellfish (e.g., crab, shrimp shells) or through fungal fermentation. The chitin is deacetylated to chitosan, then hydrolyzed to glucosamine, which is subsequently sulfated and stabilized with sodium or potassium chloride.