Other Nootropics Oral

Alpha-GPC

A highly bioavailable choline source that increases brain acetylcholine levels, used to support cognitive function and memory.

Sci.L-alpha-glycerylphosphorylcholine a-gpc alcolec gpc alpha glycerl-phosphoryl choline alpha-glycerolphosphocholine alpha glycerol phosphoryl choline alpha-glycerolphosphorylcholine alpha-glycerolphosphorylcholine powder alpha-glycerophosphatidylcholine alpha glycerophosphocholine alpha-glycerophosphocholine alpha-glycerophosphorylcholine alpha-glyceryl phosphatidylcholine alpha-glyceryl phosphatidylcholine powder alpha-glyceryl phosphory {alpha}-glycerylphosphorycholine alpha glycerylphosphorycholine alpha glyceryl phosphoryl choline alpha glyceryl phosphorylcholine alpha glycerylphosphorylcholine alpha-glyceryl phosphoryl choline alpha-glycerylphosphorylcholine alpha-glyceryl phosphoryl choline complex alpha-glycerylphosphorylcholine, powder alpha gpc alpha-gpc alpha-gpc complex alpha-gpc (l-alpha-glycerylphosphorylcholine) complex alpha gpc powder alphagrain alphasize alphasize 50% a-gpc alphasize 50wsp alphasize a-gpc alphasize alpha glycerylphosphorylcholine alphasize alpha-glyceryl phosphoryl choline alphasize alpha-glyceryl phosphorylcholine alphasize alpha gpc alphasize alpha gpc 50% alphasize gpc alphasize l-alpha-glycerylphosphorylcholine choline alfoscerate choline alphoscerate glycerophosphatidylcholine glycerophosphocholine glycerophosphorylcholine glyceryl-phosphorylcholine glycerylphosphorylcholine glyceryophosphatidyl-choline gpc gpc choline l-alpha-glycerophosphorylcholine l alpha glycerylphosphorylcholine l-alpha glyceryl phosphoryl choline l-alpha glycerylphosphorylcholine l-alpha-glyceryl phosphoryl choline l-alpha-glycerylphosphorylcholine l-alpha-glycerylphosphorylcholine hydrate l-alpha glycerylphosphorylcholine powder l-alpha gpc l-alpha-gpc proprietary blend (300 mg. per capsule) of: sn-glycero (3) phosphocholine soy stabilized l-alpha-glycerophosphatidylcholine supplying alpha-glycerylphosphorylcholine yielding 50 mg glyceryl-phosphorylcholine alpha-glyceryl phosphoryl powder alphasize l-alpha-glycerlphosphorylcholine
2 forms
Oral

About Alpha-GPC

Alpha-GPC (L-alpha-glycerylphosphorylcholine) is a cholinergic compound that serves as a highly bioavailable source of choline, crossing the blood-brain barrier to support the synthesis of acetylcholine and phosphatidylcholine in neuronal membranes. It is primarily used for cognitive support, memory enhancement, and as a potential ergogenic aid, with clinical applications in cognitive disorders such as Alzheimer's disease and stroke recovery.

Official resources

Fact sheets from the NIH Office of Dietary Supplements related to this ingredient group.

Dietary Supplement Label Database

Ingredient group data in NutriNav is aligned with the NIH Dietary Supplement Label Database (DSLD).

DSLD group id
315

At a glance

Approval status

supplement

Compare All Forms

2 forms

Compare supplement forms of Alpha-GPC by absorption quality and what your body actually gets from each:

High Moderate Low
Form Absorption Steps to absorb Notes Action
Alpha-GPC (50% or 99% purity)

Highly bioavailable choline source for brain health & cognit...

  • UNII: N91F6L3032
  • CAS: 28319-77-9
  • Label category: hybrid
 — — — View →
Choline Alfoscerate

Supports cognitive function and brain health.

  • UNII: 5M669T4A5F
  • CAS: 28319-77-9
  • Label category: synthetic
 — — — View →

Type: Nootropics

Category for Nootropics ingredients

Watch out for

Possible interactions or cautions — talk to a healthcare provider if unsure.

  • May potentiate effects of cholinergic drugs (e.g., donepezil) or supplements, potentially increasing side effects like nausea or sweating.

Potential Benefits

Benefits associated with Alpha-GPC forms:

Cognitive Enhancement Athletic Performance Cognitive Function & Memory Support Neuroprotection & Stroke Recovery Support Potential Athletic Performance Enhancement Cognitive Function

And 7 more benefits...

Potential Side Effects

Side effects associated with Alpha-GPC forms:

Headache How serious: Mild Gastrointestinal Distress How serious: low Insomnia How serious: Mild Insomnia / Restlessness How serious: low

What does the research say?

Alpha-GPC has been studied for its effects on cognitive function, memory enhancement, and potential athletic performance benefits. Key studies include clinical trials on cognitive decline and reviews on its efficacy and safety.