Typical dose
300-1200mg daily
Oral
Oral safety: very low
About this supplement
Alpha-GPC (Alpha-glycerylphosphorylcholine) is a highly bioavailable choline compound that serves as a precursor to the neurotransmitter acetylcholine and to membrane phospholipids. It exists in two common purity grades: 50% (often derived from soy lecithin) and 99% (highly purified, typically synthetic). Alpha-GPC is water-soluble and efficiently crosses the blood-brain barrier. It is used as a nootropic and dietary supplement to support cognitive function, memory, and focus, and is also studied for its potential role in athletic performance and recovery. The 99% purity form is preferred for precise dosing and research applications.
How much to take
- Typical amount
- 300-1200mg daily
- Suggested range
- 300-600mg
Potential benefits
Benefits linked to this supplement form:
Things to watch for
Possible side effects linked to this form:
Health goals
Needs and goals this form may help with:
Other forms of Alpha-GPC
Compare absorption and active amounts with sibling forms:
Technical details â–¼
Chemical ID (CAS)
28319-77-9
Formula
C8H20NO6P
Physical properties
White to off-white powder, water-soluble, hygroscopic.
How it’s made
Alpha-GPC is produced through the enzymatic hydrolysis of soy lecithin or through synthetic methods to achieve higher purity.