Typical dose
10-40 mg daily for UC-II; 500-2000 mg daily for...
Oral & topical
Oral safety: harmless
Skin safety: harmless
About this supplement
Chicken Collagen Type II is a specific form of collagen derived from the sternal cartilage of chickens, primarily composed of type II collagen fibrils. Unlike general collagen supplements (which typically contain types I and III from bovine or marine sources), chicken collagen type II is specifically targeted for joint health due to its structural similarity to human articular cartilage collagen. It is often marketed as 'undenatured type II collagen' (UC-II) when processed at low temperatures to preserve its native triple-helical conformation, which is believed to be crucial for its immunomodulatory effects in oral tolerance induction for joint comfort. This form is rich in glycosaminoglycans and chondroitin sulfate, supporting cartilage matrix integrity.
How much to take
- Typical amount
- 10-40 mg daily for UC-II; 500-2000 mg daily for hydrolyzed chicken collagen type II.
- Suggested range
- 10-40 mg daily (UC-II); 500-2000 mg daily (hydrolyzed)
Potential benefits
Benefits linked to this supplement form:
Things to watch for
Possible side effects linked to this form:
Health goals
Needs and goals this form may help with:
Other forms of Collagen
Compare absorption and active amounts with sibling forms:
Collagen
Collagen (mixed)
collagen (unknown source)
Collagen (unspecified)
Collagen Hydrolysate
Hydrolyzed for improved solubility and absorption.
Collagen II
Collagen Peptides
Hydrolyzed Chicken Collagen
Hydrolyzed Marine Collagen
Marine Collagen
Marine Collagen Peptides
Derived from fish; supports skin, joint, and bone health
Peptan (Collagen Peptides)
Hydrolyzed collagen peptides for joint, skin, and bone support.
Type II Collagen Peptides (Hydrolyzed)
Supports joint comfort and cartilage health.
Undenatured Type II Collagen
Verisol (Bioactive Collagen Peptides)
Clinically studied bioactive collagen peptides for skin, hair, and nail support.
Technical details â–¼
Chemical ID (CAS)
9007-34-5
Physical properties
Typically a fine, off-white to pale yellow powder. Hydrolyzed forms are soluble in water; native/undenatured forms are less soluble. Odorless or mild characteristic odor. Molecular weight varies: native ~300 kDa, hydrolyzed forms 2-10 kDa.
How it’s made
Extracted from chicken sternal cartilage via enzymatic hydrolysis (for hydrolyzed forms) or low-temperature processing (for undenatured UC-II). Steps include cleaning, grinding, enzymatic digestion, filtration, purification, and spray-drying. UC-II is processed below 40°C to preserve native triple-helical structure.