Typical dose
2-5 grams daily, typically divided into multiple...
Oral
Oral safety: very low
About this supplement
Beta-Alanine HCl (Hydrochloride) is the hydrochloride salt form of beta-alanine, a non-essential, non-proteinogenic amino acid. Unlike alpha-alanine, beta-alanine has the amino group attached to the beta-carbon. The hydrochloride form enhances stability and solubility. Beta-alanine is a rate-limiting precursor for carnosine synthesis in skeletal muscle. Carnosine acts as an intracellular pH buffer, helping to neutralize lactic acid accumulation during high-intensity exercise. This form is commonly used in sports nutrition supplements to improve exercise performance, particularly for activities lasting 1-4 minutes. It does not cause protein synthesis directly but increases intramuscular carnosine levels by 20-80% with chronic supplementation.
How much to take
- Typical amount
- 2-5 grams daily, typically divided into multiple smaller doses (e.g., 800-1600mg every 3-4 hours) to minimize paresthesia.
- Suggested range
- 3.2-6.4 g daily for 2-4 weeks loading, then 1.2-3.2 g daily for maintenance
Potential benefits
Benefits linked to this supplement form:
Things to watch for
Possible side effects linked to this form:
Health goals
Needs and goals this form may help with:
Other forms of Beta-Alanine
Compare absorption and active amounts with sibling forms:
Beta-Alanine (free form)
Commonly used in pre-workout and sports performance supplements. May cause trans...
carnosyn
CarnoSyn® Beta-Alanine
Clinically studied to increase muscle carnosine, buffer exercise-induced acidity...
Sustained-Release Beta-Alanine
Sustained-release form may reduce tingling side effect. Commonly used by athlete...
Technical details â–¼
Chemical ID (CAS)
2966-15-4
Formula
C3H7NO2·HCl
Physical properties
White to off-white crystalline powder. Highly soluble in water. Stable under normal storage conditions. Odorless with a slightly acidic taste.
How it’s made
Primarily produced synthetically through chemical synthesis routes, often involving the reaction of acrylonitrile with ammonia followed by hydrolysis, or via microbial fermentation using genetically modified microorganisms. The hydrochloride salt is formed by reacting beta-alanine with hydrochloric acid.