About Creatine

Creatine HCL is a form of creatine that is bound to hydrochloric acid, which is claimed to enhance its solubility compared to creatine monohydrate. This increased solubility may lead to better absorption and utilization in the body, making it a popular choice among athletes and bodybuilders for improving performance and muscle recovery.

Official resources

Fact sheets from the NIH Office of Dietary Supplements related to this ingredient group.

Dietary Supplement Label Database

Ingredient group data in NutriNav is aligned with the NIH Dietary Supplement Label Database (DSLD).

DSLD group id
397

Compare All Forms

23 forms

Compare supplement forms of Creatine by absorption quality and what your body actually gets from each:

High Moderate Low
Form Absorption Steps to absorb Notes Action
Buffered Creatine (Kre-Alkalyn)

Patented pH-buffered creatine form; claimed to be more stabl...

  • CAS: 57-00-1 (for creatine)
  • Label category: synthetic
β€” β€” β€” View β†’
Creatine β€” β€” β€” View β†’
Creatine alpha-aminobutyrate β€” β€” β€” View β†’
Creatine alpha-ketoglutarate β€” β€” β€” View β†’
Creatine beta-hydroxybutyrate β€” β€” β€” View β†’
Creatine Ethyl Ester

Less stable and less effective than creatine monohydrate; ra...

  • CAS: 862652-32-2 (hydrochloride salt common in supplements)
  • Label category: synthetic
β€” β€” β€” View β†’
Creatine gluconate β€” β€” β€” View β†’
Creatine glutamine β€” β€” β€” View β†’
Creatine HCL
  • Label category: synthetic
β€” β€” β€” View β†’
Creatine Hydrochloride (Creatine HCl)

More soluble form of creatine; often used for improved absor...

  • CAS: 870-62-2
  • Label category: synthetic
β€” β€” β€” View β†’
Creatine isoleucine β€” β€” β€” View β†’
Creatine leucinate β€” β€” β€” View β†’
Creatine leucine β€” β€” β€” View β†’
Creatine Magnesium Chelate

Chelated form for enhanced absorption; combines creatine wit...

  • Label category: synthetic
β€” β€” β€” View β†’
Creatine Malate β€” β€” β€” View β†’
Creatine Monohydrate β€” β€” β€” View β†’
Creatine Monohydrate
  • CAS: 6020-87-7
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Creatine nitrate β€” β€” β€” View β†’
Creatine Orotate β€” β€” β€” View β†’
Creatine phosphate β€” β€” β€” View β†’
Creatine Pyruvate β€” β€” β€” View β†’
Creatine valine β€” β€” β€” View β†’
Creatine-leucine β€” β€” β€” View β†’

Also appears on labels as

Additional names seen on supplement labels for forms of this ingredient (beyond the main aliases above).

CEE, Creatine hydrochloride salt, Creatine magnesium complex, Magnesium-bound creatine, Mg-creatine, pH-buffered creatine

Type: Other

Miscellaneous ingredients including fillers, binders, preservatives, artificial colors, flavors, sweeteners, and other additives found in supplements.

Absorption: Many of these ingredients are inert fillers or additives that may affect absorption of active ingredients.

Interactions: Some additives may have health concerns. Fillers may reduce absorption of other nutrients. Preservatives and artificial colors may cause adverse reactions in sensitive individuals.

Potential Benefits

Benefits associated with Creatine forms:

And 20 more benefits...

Potential Side Effects

Side effects associated with Creatine forms:

And 7 more side effects...