vitamin Vitamins Oral

Biotin

A water-soluble B-vitamin essential as a coenzyme for metabolism and energy production, commonly associated with supporting the health of hair, skin, and nails.

Sci.(3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazole-4-valeric acid biotin biotin dicalcium phosphate biotin, natural biotin, pure biotin, pure crystalline d-biotin d-biotin, natural liposomal biotin orgen-bio super biotin vitamin b7 vitamin b7, powder vitamin h
3 forms
Oral

About Biotin

Biotin, also known as vitamin B7 or vitamin H, is a water-soluble B-vitamin that functions as an essential coenzyme for five carboxylase enzymes involved in critical metabolic pathways, including fatty acid synthesis, gluconeogenesis, and amino acid catabolism. It plays a fundamental role in gene regulation and cell signaling via histone biotinylation. While often marketed for hair, skin, and nail health due to its role in keratin production, deficiency is rare in healthy individuals with a balanced diet.

Official resources

Fact sheets from the NIH Office of Dietary Supplements related to this ingredient group.

Dietary Supplement Label Database

Ingredient group data in NutriNav is aligned with the NIH Dietary Supplement Label Database (DSLD).

DSLD group id
22

At a glance

Suggested daily

30 mcg for adults (Adequate Intake).

Max safe daily

Not established; no adverse effects have been reported with high intakes, but high doses may interfere with certain lab tests.

Approval status

supplement

Compare All Forms

3 forms

Compare supplement forms of Biotin by absorption quality and what your body actually gets from each:

High Moderate Low
Form Absorption Steps to absorb Notes Action
Biotin Dicalcium Phosphate

Combined vitamin B7 and mineral supplement for metabolic and...

  • Label category: synthetic
 — — — View →
d-Biotin

Essential B-vitamin for metabolism, energy, and healthy hair...

  • UNII: 6SO6U10H04
  • CAS: 58-85-5
 — — — View →
Liposomal Biotin

Liposomal form may enhance absorption compared to standard b...

  • CAS: 58-85-5 (for biotin)
 — — — View →

Also appears on labels as

Additional names seen on supplement labels for forms of this ingredient (beyond the main aliases above).

Biotin (d-form), Biotin (vitamin B7), Biotin-CaHPO4 complex, Biotin calcium phosphate, Coenzyme R, Liposomal vitamin B7, Liposomal vitamin H, Liposome-encapsulated biotin, Vitamin B7 dicalcium phosphate

Type: Vitamins

Organic compounds essential for normal growth and nutrition. Required in small quantities in the diet because they cannot be synthesized by the body.

Absorption: Fat-soluble vitamins require dietary fat for absorption. Water-soluble vitamins are generally well-absorbed but excess amounts are excreted.

Interactions: Some vitamins can interfere with medications. Fat-soluble vitamins can accumulate in the body.

Watch out for

Possible interactions or cautions — talk to a healthcare provider if unsure.

  • High doses (>5 mg/day) can cause clinically significant interference with certain immunoassays (e.g., troponin, thyroid) leading to false results.

Potential Benefits

Benefits associated with Biotin forms:

Cofactor for Metabolic Enzymes Treatment of Biotin Deficiency Improvement of Brittle Nails Hair Health Support Skin Health Support Skin Health

And 13 more benefits...

Potential Side Effects

Side effects associated with Biotin forms:

Allergic Reactions How serious: Mild Interference with Lab Tests How serious: high Acne Eruptions How serious: low Acne How serious: Mild Lab Test Interference How serious: Moderate Gastrointestinal Discomfort How serious: low

And 4 more side effects...

What does the research say?

Biotin is essential for various metabolic processes and is involved in the synthesis of fatty acids and glucose. While its role in hair, skin, and nail health is widely recognized, scientific evidence supporting its effectiveness in supplementation for these purposes is limited in individuals without deficiency.