About Ashwagandha

Ashwagandha (Withania somnifera) is a perennial shrub in the Solanaceae family, traditionally used in Ayurvedic medicine as an adaptogen. Its bioactive constituents, primarily withanolides, are credited with modulating stress response via the hypothalamic-pituitary-adrenal (HPA) axis, supporting cognitive function, and promoting resilience. Modern research investigates its potential effects on cortisol levels, anxiety, sleep quality, and physical performance.

Official resources

Fact sheets from the NIH Office of Dietary Supplements related to this ingredient group.

Dietary Supplement Label Database

Ingredient group data in NutriNav is aligned with the NIH Dietary Supplement Label Database (DSLD).

DSLD group id
11

At a glance

Approval status

supplement

Compare All Forms

8 forms

Compare supplement forms of Ashwagandha by absorption quality and what your body actually gets from each:

High Moderate Low
Form Absorption Steps to absorb Notes Action
ashwagandha ksm-66
  • Label category: natural
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ashwagandha leaf extract
  • Label category: natural
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ashwagandha root extract
  • Label category: natural
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Ashwagandha Root Extract (standardized to withanolides)

Standardized adaptogen for stress support and vitality.

  • UNII: 5C5YCD25W2
  • CAS: 90147-49-6
  • Label category: natural
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Ashwagandha Root Powder

Traditional adaptogen used for stress support, energy, and v...

  • UNII: 5C5YCD25WU
  • CAS: 977038-92-0 (for plant material); various for specific withanolides
  • Label category: natural
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KSM-66 Ashwagandha

Standardized root extract. Supports stress relief, mental fo...

  • CAS: 90147-49-6
  • Label category: natural
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Sensoril Ashwagandha

Standardized adaptogen for stress relief, mental clarity, an...

  • CAS: 84650-15-7
  • Label category: natural
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Shoden Ashwagandha

Standardized extract. Supports stress response and mental fo...

  • CAS: 90045-22-6
  • Label category: natural
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Also appears on labels as

Additional names seen on supplement labels for forms of this ingredient (beyond the main aliases above).

Asgandh, Withania Root, Withania root extract

Type: Botanicals

Category for Botanicals ingredients

Watch out for

Possible interactions or cautions β€” talk to a healthcare provider if unsure.

  • May interact with sedatives, thyroid medications, and immunosuppressants.

Potential Benefits

Benefits associated with Ashwagandha forms:

And 18 more benefits...

Potential Side Effects

Side effects associated with Ashwagandha forms:

And 2 more side effects...

What does the research say?

Numerous studies have demonstrated the efficacy of ashwagandha in reducing stress, enhancing cognitive function, and improving physical performance. Clinical trials have shown that KSM-66 can significantly lower cortisol levels and improve overall quality of life.