Showing 24 of 372 side effects
IgE Allergy (rare)
ModerateCauses or contributes to IgE Allergy (rare).
Excessive isolated BCAA intake without adequate intake of other essential amino acids could theoretically disrupt amino...
Increased Bleeding Risk
mediumMay inhibit platelet aggregation and increase risk of bleeding, especially when combined with anticoagulants (e.g., warf...
Due to catecholamine synthesis, very high doses could theoretically increase blood pressure in sensitive individuals.
Causes or contributes to Increased Body Temperature.
Rapid conversion to creatinine in the body places an unnecessary filtration burden on the kidneys and can falsely elevat...
Increased Heart Rate
MildCauses or contributes to Increased Heart Rate.
Acutely elevates heart rate and blood pressure, which may be concerning for individuals with cardiovascular conditions o...
Ineffectiveness
mediumClinical studies show it is significantly less effective than creatine monohydrate at elevating intramuscular creatine l...
Infant Botulism Risk
highLike all honey products, may contain Clostridium botulinum spores and should NOT be given to infants under one year old.
Infections
mediumIn rare cases, individuals with compromised immune systems may be at risk of infections from probiotic strains.
Inflammatory Effects
MildCauses or contributes to Inflammatory Effects.
Potential for overstimulation or sleep disturbances if taken too close to bedtime.
Especially with high doses or prolonged use, may cause overstimulation, insomnia, nervousness, or headaches.
Insomnia & Sleep Disruption
mediumCan delay sleep onset, reduce sleep quality, and increase nighttime awakenings, especially when consumed later in the da...
May cause difficulty sleeping or agitation, especially at high doses or if taken late in the day.
May cause overstimulation, jitteriness, or difficulty sleeping if taken in high doses or too late in the day.
High doses or evening consumption may cause sleep disturbances due to potential stimulatory effects.
Insulin Resistance
ModerateCauses or contributes to Insulin Resistance.
Causes or contributes to Insulin Resistance (some isomers, debated).
Theoretical concern about affecting insulin sensitivity at very high doses, though clinical significance in typical supp...
Insulin Resistance Risk
mediumChronic, very high intake may potentially contribute to insulin resistance in sedentary populations, though evidence is...
Causes or contributes to Insulin Sensitivity Issues.