Showing 24 of 372 side effects
May interfere with vitamin K antagonist anticoagulants like warfarin, reducing their effectiveness. Patients on such med...
Potential Drug Interactions
mediumMay interact with antidepressants (SSRIs, MAOIs), stimulants, diabetes medications, or blood thinners. Consultation with...
Potential for Intolerance
mediumIndividuals with severe Irritable Bowel Syndrome (IBS) or FODMAP sensitivity may experience exacerbated symptoms.
In theory, very high doses could lead to increased glutamate levels, with a risk of neuroexcitatory effects, though this...
Potential for Nitrogen Load
mediumIn individuals with severe liver or kidney impairment, high doses could contribute to excess nitrogen burden. Use with c...
Contains isoflavones (phytoestrogens). Theoretical concerns exist regarding effects on thyroid function or estrogen-sens...
Potential Insulin Resistance
mediumSome animal and observational studies suggest chronic high intake may be associated with insulin resistance, though huma...
Individuals with Amyotrophic Lateral Sclerosis (ALS) or advanced liver disease (e.g., cirrhosis with hepatic encephalopa...
May interfere with vitamin K antagonist anticoagulants like warfarin, reducing their effectiveness. Requires medical sup...
As a precursor to thyroid hormones, high doses could theoretically interfere with thyroid function or thyroid medication...
A theoretical concern for individuals with pre-existing kidney impairment, though creatine is generally considered safe...
Rare cases of elevated liver enzymes have been reported; monitoring is advised with pre-existing liver conditions.
High doses of folate can mask the symptoms of vitamin B12 deficiency, potentially leading to neurological damage if left...
In individuals with severe liver disease, renal impairment, or certain inborn errors of metabolism (e.g., Reye's syndrom...
Theoretical concern in individuals with severe liver disease, certain cancers (e.g., those dependent on glutamine metabo...
In very sensitive individuals, topical application at high concentrations may cause mild irritation or dryness, though i...
May increase thyroid hormone levels; caution is advised for individuals with thyroid disorders, especially hyperthyroidi...
May increase thyroid hormone levels (T4). Caution advised for individuals with thyroid disorders or those taking thyroid...
Rapid administration or use in patients with compromised cardiac or renal function can cause circulatory overload.
Very rare cases of allergic reaction, particularly with natto-sourced MK-7 in individuals sensitive to soy or Bacillus s...
Rare Allergy
MildCauses or contributes to Rare Allergy.
Phytic acid present in oat bran can bind to minerals like iron, zinc, and calcium, potentially reducing their absorption...
Causes or contributes to Reduced Nutrient Absorption.