High doses of niacin can cause liver inflammation and damage, potentially leading to liver failure. Monitoring liver function is crucial during high-dose niacin supplementation.
Prolonged use of high doses of niacin (Vitamin B3 or nicotinic acid) can induce liver damage. This can manifest as liver inflammation, leading to elevated liver enzymes detectable in blood tests. Observable symptoms may include jaundice (yellowing of skin and eyes), hepatomegaly (enlarged liver), abdominal pain, nausea, vomiting, fatigue, and dark urine. In severe cases, this damage can progress to liver failure. Regular monitoring of liver function is recommended for individuals undergoing high-dose niacin supplementation.
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This information is for educational purposes only. Always consult with a healthcare professional before starting any new supplement regimen, especially if you experience any side effects.