Glutathione (Topical)

Outside Body
Outside: Harmless

Topical glutathione is an antioxidant used in skincare products primarily for its potential skin-brightening and anti-aging effects. It works by inhibiting melanin production and neutralizing free rad...

Topical glutathione is an antioxidant used in skincare products primarily for its potential skin-brightening and anti-aging effects. It works by inhibiting melanin production and neutralizing free radicals. While generally considered safe for topical use, some individuals may experience skin irritation or allergic reactions. The efficacy of topical glutathione can vary widely depending on the formulation, concentration, and individual skin characteristics. Further research is needed to fully understand its long-term effects and optimal usage.

Key Information

Outside Body Harmful Score

Harmless

Common Dosage

Dosage varies greatly depending on the formulation and intended use. Follow product instructions, which typically involve applying a cream or serum containing glutathione 1-2 times daily.

Source Type

natural

Production Process

Glutathione for topical applications is often produced through fermentation processes using microorganisms like yeast. It can also be synthesized chemically, but fermentation is more common for large-scale production.

Use Type

Outside Body

Potential Benefits

Antioxidant protection defends the body against free radical damage, reducing the risk of chronic diseases and promoting overall cellular health. This is achieved by neutralizing unstable molecules that cause oxidative stress and cellular damage.

3/5

Bakuchiol reduces acne by decreasing inflammation, inhibiting acne-causing bacteria, and preventing clogged pores. Its anti-inflammatory and antibacterial properties help improve skin clarity and reduce acne lesions.

2/5

Glutathione inhibits melanin production, leading to a lighter skin tone, reduced hyperpigmentation, and improved skin radiance. Effectiveness varies based on product, concentration, and individual skin.

3/5

Possible Side Effects

Skin Irritation

Skin irritation involves symptoms like redness, itching, and rashes due to contact with irritants, allergens, or environmental factors. Severity varies based on the cause, individual sensitivity, and affected area; persistent cases may lead to secondary infections.

low
Allergic Reactions

Allergic reactions are hypersensitivity responses to allergens, ranging from mild skin irritation to life-threatening anaphylaxis. Symptoms vary widely and are caused by an immune response.

medium

Scientific Evidence

Clinical, Cosmetic and Investigational Dermatology 2014:7 267–274, The Journal of Clinical and Aesthetic Dermatology. 2017 Jan; 10(1): 31–34, Journal of Dermatological Treatment, Volume 31, 2020 - Issue 5

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