About Glutathione

Topical glutathione is an antioxidant used in skincare products primarily for its potential skin-brightening and anti-aging effects. It works by inhibiting melanin production and neutralizing free radicals. While generally considered safe for topical use, some individuals may experience skin irritation or allergic reactions. The efficacy of topical glutathione can vary widely depending on the formulation, concentration, and individual skin characteristics. Further research is needed to fully understand its long-term effects and optimal usage.

Key Information

Category
Specialty Compounds
Use Type
Outside Body

Compare All Forms

Compare different forms of Glutathione by bioavailability, conversion rates, and active ingredient content:

Form Tier Steps Glutathione
(mg)
Bioavailability Action
Glutathione (Oral) Tier 2 1 — Moderate bioavailability form. Reliable form that works well but requires 1-2 step conversions by the body. Good balance of cost and effectiveness. View →
Glutathione (Topical) Tier 2 1 — Moderate bioavailability form. Reliable form that works well but requires 1-2 step conversions by the body. Good balance of cost and effectiveness. View →

Scientific Evidence

Clinical, Cosmetic and Investigational Dermatology 2014:7 267–274, The Journal of Clinical and Aesthetic Dermatology. 2017 Jan; 10(1): 31–34, Journal of Dermatological Treatment, Volume 31, 2020 - Issue 5