Typical dose
400-800 mcg daily
Oral
Oral safety: very low
About this supplement
Vitamin B9, also known as methyltetrahydrofolate, is the active form of folate, a water-soluble B vitamin that plays a crucial role in DNA synthesis, repair, and methylation. It is essential for cell division and is particularly important during periods of rapid growth such as pregnancy and fetal development. Methyltetrahydrofolate is involved in the metabolism of homocysteine, an amino acid that, at elevated levels, is associated with cardiovascular diseases.
How much to take
- Typical amount
- 400-800 mcg daily
- Suggested range
- 400-800 mcg
Potential benefits
Benefits linked to this supplement form:
Things to watch for
Possible side effects linked to this form:
Health goals
Needs and goals this form may help with:
Other forms of Vitamin B9
Compare absorption and active amounts with sibling forms:
5-Methyltetrahydrofolate (5-MTHF)
Vitamin B9 (5-Methyltetrahydrofolate)
Vitamin B9 (Calcium Folinate)
Vitamin B9 (calcium methylfolate)
Vitamin B9 (calcium methyltetrahydrofolate)
Vitamin B9 (Folate)
Vitamin B9 (folic acid)
Vitamin B9 (folic acid/folate)
Vitamin B9 (folinic acid)
Vitamin B9 (methylfolate)
Vitamin B9 (Mixed)
Vitamin B9 (unspecified)
Technical details â–¼
Chemical ID (CAS)
118196-08-6
Formula
C20H24N7O6
Physical properties
Methyltetrahydrofolate is a yellow to orange crystalline powder that is soluble in water. It is sensitive to heat and light.
How it’s made
Methyltetrahydrofolate can be synthesized from folic acid through enzymatic reduction processes or can be derived from natural sources such as leafy green vegetables and legumes.