Typical dose
100-400 mcg daily
Oral
Oral safety: very low
About this supplement
Vitamin B9, also known as 5-Methyltetrahydrofolate (5-MTHF), is the active form of folate, a B-vitamin that plays a crucial role in DNA synthesis, repair, and methylation. It is essential for the production of red blood cells and the proper functioning of the nervous system. Unlike folic acid, which must be converted into its active form in the body, 5-MTHF is readily utilized by the body, making it a preferred form of folate supplementation.
How much to take
- Typical amount
- 100-400 mcg daily
- Suggested range
- 400-800 mcg daily
Potential benefits
Benefits linked to this supplement form:
Things to watch for
Possible side effects linked to this form:
Health goals
Needs and goals this form may help with:
Other forms of Vitamin B9
Compare absorption and active amounts with sibling forms:
5-Methyltetrahydrofolate (5-MTHF)
Vitamin B9 (Calcium Folinate)
Vitamin B9 (calcium methylfolate)
Vitamin B9 (calcium methyltetrahydrofolate)
Vitamin B9 (Folate)
Vitamin B9 (folic acid)
Vitamin B9 (folic acid/folate)
Vitamin B9 (folinic acid)
Vitamin B9 (methylfolate)
Vitamin B9 (methyltetrahydrofolate)
Vitamin B9 (Mixed)
Vitamin B9 (unspecified)
Technical details â–¼
Chemical ID (CAS)
118196-08-6
Formula
C20H24N7O6
Physical properties
5-Methyltetrahydrofolate is a yellow to orange crystalline powder that is soluble in water. It is sensitive to heat and light, requiring careful storage conditions.
How it’s made
5-Methyltetrahydrofolate is typically produced through fermentation processes using specific strains of bacteria or through chemical synthesis.