Typical dose

200-600mg daily

Oral Oral safety: harmless

About this supplement

Sulbutiamine is a synthetic derivative of thiamine (Vitamin B1) that is designed to enhance the bioavailability of thiamine in the body. It is composed of two thiamine molecules linked by a disulfide bond, which allows it to cross the blood-brain barrier more effectively than regular thiamine. Sulbutiamine is often used to improve cognitive function, reduce fatigue, and enhance mood.

How much to take

Typical amount
200-600mg daily
Suggested range
200-600 mg

Potential benefits

Benefits linked to this supplement form:

Things to watch for

Possible side effects linked to this form:

Health goals

Needs and goals this form may help with:

Other forms of Vitamin B1

Compare absorption and active amounts with sibling forms:

Technical details â–¼

Chemical ID (CAS)

3286-46-2

Physical properties

White to off-white crystalline powder, soluble in water, slightly soluble in alcohol.

How it’s made

Sulbutiamine is synthesized through a chemical process that involves the modification of thiamine to create the disulfide bond.