Typical dose
Used as a sweetening agent in very small quantit...
Oral
Oral safety: very low
About this supplement
Sodium saccharin is the sodium salt of saccharin, a synthetic, non-nutritive, high-intensity artificial sweetener. It is approximately 300-500 times sweeter than sucrose (table sugar) but contributes no calories or carbohydrates. It is heat-stable and does not promote tooth decay. While widely used as a sugar substitute in foods, beverages, and tabletop sweeteners, its use in dietary supplements is typically as a flavoring agent to improve palatability. Historically, it was linked to bladder cancer in rodent studies, leading to a warning label requirement (now removed), but subsequent extensive human studies have not confirmed this risk, and major health agencies consider it safe for human consumption within established Acceptable Daily Intake (ADI) limits.
How much to take
- Typical amount
- Used as a sweetening agent in very small quantities, typically milligrams per serving. Not a therapeutic ingredient; dosage is for taste only.
- Suggested range
- No therapeutic dosage. Use is governed by an Acceptable Daily Intake (ADI) of 5 mg/kg body weight per day (as saccharin).
Potential benefits
Benefits linked to this supplement form:
Things to watch for
Possible side effects linked to this form:
Health goals
Needs and goals this form may help with:
Other forms of Saccharin
Compare absorption and active amounts with sibling forms:
Technical details â–¼
Chemical ID (CAS)
128-44-9
Physical properties
White crystalline powder or colorless crystals. Odorless or with a faint aromatic odor. Very soluble in water; slightly soluble in ethanol. Has an intensely sweet taste, with a metallic or bitter aftertaste at high concentrations.
How it’s made
Synthesized chemically via the Remsen-Fahlberg process, starting with toluene. The process involves sulfonation of toluene, followed by oxidation and cyclization to form saccharin acid. The acid is then neutralized with sodium hydroxide or sodium bicarbonate to produce the sodium salt, which is purified by crystallization.