Typical dose
50-400 mg daily, typically 30-60 minutes before...
Oral
Oral safety: low
About this supplement
Caffeine anhydrous is the dehydrated, powdered form of caffeine, containing less than 0.5% water. It is a central nervous system stimulant belonging to the methylxanthine class. Unlike caffeine from natural sources (coffee, tea), it is a highly concentrated, purified chemical compound used primarily in dietary supplements, energy products, and pharmaceuticals for its stimulant and ergogenic effects. It works primarily by antagonizing adenosine receptors in the brain, leading to increased alertness, reduced perception of effort, and enhanced fat oxidation during exercise.
How much to take
- Typical amount
- 50-400 mg daily, typically 30-60 minutes before exercise or for alertness. Doses above 400-500 mg daily are not recommended for general adults.
- Suggested range
- 100-300 mg per serving, not to exceed 400 mg daily for healthy adults
Potential benefits
Benefits linked to this supplement form:
Things to watch for
Possible side effects linked to this form:
Health goals
Needs and goals this form may help with:
Other forms of Caffeine
Compare absorption and active amounts with sibling forms:
Caffeine alpha-ketoglutarate
Caffeine Citrate
Pharmaceutical-grade stimulant used primarily for neonatal apnea. Also found in...
Caffeine pterostilbene
Dicaffeine Malate
Often marketed for sustained energy and focus with reduced side effects.
Natural Caffeine (from Coffea/Guarana)
Natural stimulant from coffee beans or guarana. May improve alertness and exerci...
Sustained/Extended-Release Caffeine
Provides prolonged energy and focus; may reduce jitters and crash compared to st...
Technical details â–¼
Chemical ID (CAS)
58-08-2
Formula
C8H10N4O2
Physical properties
White crystalline powder or needles. Odorless with a bitter taste. Soluble in hot water, chloroform, and moderately soluble in ethanol. Melting point: 235-238°C. Hygroscopic.
How it’s made
Primarily produced synthetically via methylation of theobromine or xanthine. Also extracted from natural sources like coffee beans or tea leaves followed by chemical processing and dehydration to remove water, resulting in the 'anhydrous' form. Industrial synthesis from dimethylurea and malonic acid is common.