Creatine HCL

Inside Body
Inside: Harmless

Creatine HCL aims to enhance solubility and absorption of creatine for improved strength and muscle growth.

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Creatine HCL aims to enhance solubility and absorption of creatine for improved strength and muscle growth.

Creatine HCL is a synthetically produced form of creatine bonded with hydrochloric acid, aimed at improving solubility and absorption compared to creatine monohydrate. While some evidence suggests potential benefits in absorption and reduced bloating, clinical evidence for significantly superior performance outcomes compared to creatine monohydrate is limited. It is used to boost strength, power, and muscle growth through increased ATP availability. Common side effects can include gastrointestinal issues and water retention. Dosage is generally lower than creatine monohydrate due to purportedly enhanced absorption, typically ranging from 1.5-3g daily.

Key Information

Inside Body Harmful Score

Harmless

Common Dosage

1.5-3g daily

Source Type

synthetic

Production Process

Creatine HCL is produced by chemically bonding creatine with hydrochloric acid in a laboratory setting. This process results in a creatine salt that is more soluble in water.

Use Type

Inside Body

Potential Benefits

Muscle growth (hypertrophy) is primarily driven by resistance training, adequate protein intake, and sufficient caloric surplus, leading to increased muscle size and strength. Hormonal factors, rest, and genetics influence the rate and extent of this process.

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Strength increase refers to the enhanced ability of muscles to exert force, resulting from muscle adaptations through resistance training, proper nutrition, and adequate rest. This improvement benefits daily activities, athletic performance, and overall physical health.

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Creatine HCL is claimed to have superior solubility compared to creatine monohydrate, leading to improved absorption and reduced gastrointestinal distress. This potentially allows for better utilization of creatine by muscle cells.

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Creatine HCL may improve muscle strength and power output during high-intensity exercise by boosting ATP availability. Its effectiveness compared to creatine monohydrate is still under investigation.

3/5

Possible Side Effects

Water Retention

Water retention, or edema, is the buildup of excess fluid in the body, causing swelling, bloating, and potential discomfort. It can be triggered by various factors including hormonal changes, medication, or underlying health conditions.

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None

Hypothetically, this substance can cause mild skin irritation with redness, itching, and burning at the application site, resolving on its own.

low
Gastrointestinal Distress

Gastrointestinal distress involves digestive discomfort like bloating, diarrhea, cramps, nausea, and vomiting. Severity varies based on individual factors and can be triggered by irritation or inflammation of the digestive tract.

low
Muscle Cramps

Creatine supplementation is sometimes associated with muscle cramps, likely due to electrolyte imbalance, dehydration, or increased exercise intensity. The link is not definitively proven, and individual susceptibility varies.

low
Gastrointestinal Issues

Gastrointestinal issues include nausea, diarrhea, abdominal discomfort, and vomiting, potentially stemming from altered gut motility, microbiota changes, or irritation. While often mild, persistent symptoms necessitate evaluation, and contributing factors like pre-existing conditions should be considered.

low

Scientific Evidence

Key scientific sources and studies comparing creatine HCL to creatine monohydrate in terms of absorption, muscle performance, and side effects (search for studies on PubMed, Google Scholar)

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