About Nicotinamide Riboside
Nicotinamide Riboside (NR) is a synthetic form of vitamin B3 and a precursor to NAD+, a critical coenzyme involved in numerous cellular processes including energy production, DNA repair, and overall cellular health. Supplementation with NR aims to elevate NAD+ levels, potentially resulting in benefits such as enhanced energy metabolism, anti-aging effects, and neuroprotection. NR is generally considered safe for most individuals, although some may experience mild side effects. While research is ongoing, the potential benefits of NR in promoting healthy aging and preventing age-related diseases are promising. Long-term studies are still needed to fully understand the full spectrum of benefits and potential risks associated with NR supplementation.
Key Information
Compare All Forms
Compare different forms of Nicotinamide Riboside by bioavailability, conversion rates, and active ingredient content:
| Form | Tier | Steps |
Nicotinamide Riboside Activity (mcg) |
Bioavailability | Action |
|---|---|---|---|---|---|
| Nicotinamide Riboside (NR) | Tier 3 | 3 | — | Basic/low bioavailability form. Cheap raw material with poor absorption or high GI distress. Often poorly utilized by the body, requires 3+ conversion steps. | View → |
Scientific Evidence
Studies on NR and NAD+ in humans and animal models, including clinical trials assessing the effects of NR supplementation on NAD+ levels and various health outcomes. Specific sources include research articles published in peer-reviewed scientific journals such as Nature, Cell Metabolism, and the Journal of Nutritional Biochemistry.