About N-Acetyl Cysteine

N-Acetyl Cysteine (NAC) is a synthetic derivative of the amino acid L-cysteine, primarily utilized as a glutathione precursor to bolster antioxidant defenses and detoxification processes. Its established uses include mucolytic action for respiratory ailments and serving as a crucial antidote for acetaminophen overdose. Emerging research explores its potential in supporting mental health and fertility. While generally considered safe, common side effects include gastrointestinal distress, and individuals should consult healthcare providers before use, especially those with pre-existing conditions or taking other medications.

Key Information

Category
Specialty Compounds
Use Type
Inside Body

Compare All Forms

Compare different forms of N-Acetyl Cysteine by bioavailability, conversion rates, and active ingredient content:

Form Tier Steps N-Acetyl Cysteine
(mg)
Bioavailability Action
N-Acetyl Cysteine (NAC)

N-Acetyl Cysteine (NAC) is a glutathione precursor, used as...

Tier 3 3 — Basic/low bioavailability form. Cheap raw material with poor absorption or high GI distress. Often poorly utilized by the body, requires 3+ conversion steps. View →

Scientific Evidence

Numerous studies available on PubMed and other scientific databases. Key research areas include glutathione synthesis, mucolytic effects, acetaminophen toxicity, mental health applications (OCD, depression), and fertility (PCOS, sperm quality). Examples include studies published in journals such as 'Free Radical Biology and Medicine', 'Chest', 'Clinical Toxicology', 'Journal of Clinical Psychiatry', and 'Human Reproduction'.