About FD&C Yellow #5

FD&C Yellow #5 (Tartrazine) is a synthetic azo dye widely used as a yellow colorant in food, medications, and supplements. While effective in imparting color, it is a known allergen for some individuals, potentially causing hives, itching, and more severe reactions. Its association with hyperactivity in children is debated, but some evidence suggests a possible link, particularly when combined with other artificial additives. Due to potential adverse effects, regulatory agencies monitor and control its use.

Key Information

Category
Excipients
Use Type
Inside Body
Average Rating
1.8 /5

Compare All Forms

Compare different forms of FD&C Yellow #5 by bioavailability, conversion rates, and active ingredient content:

Form Tier Steps FD&C Yellow #5
(mg)
Bioavailability Action
FD&C Yellow #5 (Tartrazine) Tier 3 3 — Basic/low bioavailability form. Cheap raw material with poor absorption or high GI distress. Often poorly utilized by the body, requires 3+ conversion steps. View →

Scientific Evidence

https://www.fda.gov/food/food-additives-petitions/color-additives-history; https://www.efsa.europa.eu/en/efsajournal/pub/3844; https://pubmed.ncbi.nlm.nih.gov/17825405/