About Diindolylmethane
Diindolylmethane (DIM) is a naturally occurring compound formed during the digestion of indole-3-carbinol (I3C), which is found in cruciferous vegetables. It is available as a dietary supplement and is believed to influence estrogen metabolism, potentially shifting the balance towards more beneficial estrogen metabolites. While research is ongoing, DIM is also investigated for its antioxidant, anti-inflammatory, and potential anticancer properties. Common side effects are generally mild.
Key Information
Compare All Forms
Compare different forms of Diindolylmethane by bioavailability, conversion rates, and active ingredient content:
| Form | Tier | Steps |
Diindolylmethane (mg) |
Bioavailability | Action |
|---|---|---|---|---|---|
| Diindolylmethane (DIM) | Tier 1 | 0 | — | High bioavailability form. Body-ready, bypasses conversion steps. Maximum absorption, lowest waste. | View → |
Scientific Evidence
Bradlow HL, Sepkovic DW, Telang NT, Osborne MP. Indole-3-carbinol. Adv Exp Med Biol. 1999;472:183-92. PMID: 10719748; Zeligs MA, Fulfaro F, Carducci MA. Review of clinical studies of diindolylmethane (DIM) in cancer prevention and treatment. Nutr Cancer. 2023;75(6):1341-1353. doi: 10.1080/01635581.2022.2113924. Epub 2022 Aug 25. PMID: 36001585.