About CoQ10
Ubiquinol is the reduced, active antioxidant form of Coenzyme Q10 (CoQ10), a naturally occurring compound essential for cellular energy production, particularly within the mitochondria. As we age, the body's ability to convert CoQ10 (ubiquinone) to ubiquinol decreases, making direct ubiquinol supplementation potentially more beneficial for older adults and those with certain health conditions. Ubiquinol offers superior bioavailability compared to ubiquinone and is primarily known for its role in supporting cardiovascular health, neurological function, fertility, and reducing statin-induced side effects. While generally safe, some individuals may experience mild gastrointestinal issues.
Key Information
Compare All Forms
Compare different forms of CoQ10 by bioavailability, conversion rates, and active ingredient content:
| Form | Tier | Steps |
CoQ10 (mg) |
Bioavailability | Action |
|---|---|---|---|---|---|
|
CoQ10 (Ubiquinol)
Ubiquinol, the active form of CoQ10, boosts cellular energy... |
Tier 1 | 0 | — | High bioavailability form. Body-ready, bypasses conversion steps. Maximum absorption, lowest waste. | View → |
Scientific Evidence
Crane, F. L. (2001). Biochemical functions of coenzyme Q10. Journal of the American College of Nutrition, 20(6), 591-598.
Littarru, G. P., & Tiano, L. (2007). Bioenergetic and antioxidant properties of coenzyme Q10: recent developments. Molecular biotechnology, 37(1), 31-37.
Soja, A. M., & Mortensen, S. A. (1997). Coenzyme Q10 in cardiovascular disease. Molecular aspects of medicine, 18 Suppl, S159-S168.
Arenas-Jal, M., Suñé-Negre, J. M., & GarcÃa-Montoya, E. (2020). Coenzyme Q10 supplementation: Clinical implications and bioavailability. Antioxidants, 9(7), 649.
Littarru, G. P., & Tiano, L. (2007). Bioenergetic and antioxidant properties of coenzyme Q10: recent developments. Molecular biotechnology, 37(1), 31-37.
Soja, A. M., & Mortensen, S. A. (1997). Coenzyme Q10 in cardiovascular disease. Molecular aspects of medicine, 18 Suppl, S159-S168.
Arenas-Jal, M., Suñé-Negre, J. M., & GarcÃa-Montoya, E. (2020). Coenzyme Q10 supplementation: Clinical implications and bioavailability. Antioxidants, 9(7), 649.