About Azelaic Acid Derivative

Potassium Azeloyl Diglycinate is a water-soluble, synthetic derivative of azelaic acid designed for improved bioavailability and tolerability in skincare applications. It is primarily used topically for its skin brightening, sebum-controlling, anti-inflammatory, and hydrating properties. Preliminary to moderate scientific evidence supports these benefits. While generally well-tolerated, some individuals may experience mild skin irritation or dryness.

Key Information

Category
Minerals
Use Type
Outside Body

Compare All Forms

Compare different forms of Azelaic Acid Derivative by bioavailability, conversion rates, and active ingredient content:

Form Tier Steps Elemental Azelaic Acid Derivative
(mg)
Bioavailability Action
Azelaic Acid Derivative (Potassium Azeloyl Diglycinate)

Potassium Azeloyl Diglycinate improves azelaic acid's tolera...

Tier 3 3 14.0%

(400mg = 56mg)

Basic/low bioavailability form. Cheap raw material with poor absorption or high GI distress. Often poorly utilized by the body, requires 3+ conversion steps. View →

Scientific Evidence

Limited number of published studies available. Evidence consists primarily of in-vitro studies and small clinical trials. More robust research is needed to confirm efficacy and long-term safety. Studies focusing on azelaic acid provide indirect support.