Apigenin, a flavonoid from various plants, exhibits anti-inflammatory, antioxidant, and anxiolytic effects, requiring professional consultation.
Apigenin is a naturally occurring flavonoid found in various plants with potential anti-inflammatory, antioxidant, anxiolytic, and anti-cancer properties. It is typically extracted from plants like chamomile, parsley, and celery. Common dosages range from 50-500mg daily. Side effects are generally mild, with drowsiness being the most frequently reported. Further research is needed to fully understand its efficacy and safety profile in humans. Consultation with a healthcare professional is recommended before use, especially for individuals with pre-existing conditions or taking medications.
Key Information
Inside Body Harmful Score
Common Dosage
50-500mg daily
Source Type
natural
Production Process
Extracted from plants such as chamomile, parsley, and celery using various methods like solvent extraction or supercritical fluid extraction. Can also be synthesized chemically, though less common for supplement production.
Use Type
Inside BodyPotential Benefits
This benefit reduces inflammation by modulating inflammatory pathways and inhibiting pro-inflammatory cytokines, resulting in reduced pain, swelling, and improved function. It is beneficial for conditions like arthritis, inflammatory bowel disease, cardiovascular disease, and skin conditions.
Antioxidants neutralize harmful free radicals, preventing cellular damage and reducing oxidative stress, which can contribute to overall health and disease prevention. They work by donating electrons to stabilize free radicals and supporting antioxidant enzyme systems.
Apigenin may reduce anxiety by interacting with GABA receptors in the brain, which promotes relaxation. This interaction could help regulate neuronal excitability and reduce anxiety symptoms.
Apigenin exhibits potential anti-cancer properties by inhibiting cancer cell growth, inducing apoptosis, and preventing angiogenesis in preclinical studies. Further human research is needed to confirm its effectiveness.
Possible Side Effects
Drowsiness is a state of impaired alertness characterized by a strong desire to sleep and reduced responsiveness. It can cause difficulty concentrating, decreased reaction time, and impaired judgment.
Allergic reactions are hypersensitivity responses to allergens, ranging from mild skin irritation to life-threatening anaphylaxis. Symptoms vary widely and are caused by an immune response.
Drug interactions can alter a drug's effectiveness, leading to either increased risk of blood clots or bleeding, particularly with anticoagulants. Monitoring is essential to manage these interactions.
Scientific Evidence
Limited human studies available. In vitro and animal studies suggest various health benefits. Key areas of research include its impact on inflammation, oxidative stress, anxiety, and cancer cell behavior. More robust clinical trials are necessary to establish definitive conclusions.
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