Trimethylaminuria results in a fishy body odor due to the body's inability to break down trimethylamine. High doses of betaine may exacerbate the condition in susceptible individuals.
Trimethylaminuria (TMAU), also known as fish odor syndrome, is a metabolic disorder where the body is unable to properly metabolize trimethylamine (TMA). TMA is a chemical compound produced in the intestine during the digestion of choline, carnitine, and lecithin found in foods. Individuals with TMAU lack or have a deficiency in the enzyme flavin-containing monooxygenase 3 (FMO3), which is responsible for converting TMA into odorless trimethylamine oxide (TMAO). As a result, TMA accumulates in the body and is released in sweat, urine, and breath, causing a characteristic fishy odor. In some cases, it is exacerbated by high doses of betaine.
Key Information
Severity
Low
Associated Ingredients
1 ingredient
Associated Ingredients
Betaine
Betaine, also known as trimethylglycine (TMG), is a naturally occurring compound found in sources su...
Important Safety Information
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