Serotonin syndrome is a potentially life-threatening condition caused by excessive serotonin levels, often triggered by combining 5-HTP with other serotonergic medications. Symptoms range from mild to severe and require immediate medical attention.
Serotonin syndrome is a potentially life-threatening condition resulting from excessive serotonin activity in the central nervous system. It most commonly occurs when two or more serotonergic drugs are used together, such as 5-HTP in combination with selective serotonin reuptake inhibitors (SSRIs), monoamine oxidase inhibitors (MAOIs), tricyclic antidepressants (TCAs), or other medications that enhance serotonin levels. Symptoms can range from mild (tremor, diarrhea) to severe (muscle rigidity, hyperthermia, seizures, coma, and even death). Early recognition and prompt medical intervention are crucial to prevent serious complications.
Key Information
Severity
High
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