Hypercalcemia (with Collagen peptides)

High-dose collagen peptide supplementation can potentially lead to hypercalcemia, especially in individuals with kidney disease or those also taking calcium supplements. Symptoms can range from mild fatigue to severe cardiac arrhythmias.

Hypercalcemia, or elevated calcium levels in the blood, can occur as a potential side effect of high-dose collagen peptide supplementation. This is particularly relevant in individuals with pre-existing kidney disease, as impaired kidney function can hinder calcium excretion. Concomitant use of calcium supplements alongside high-dose collagen peptides may further exacerbate the risk. Symptoms of hypercalcemia can range from mild (fatigue, nausea, constipation) to severe (confusion, kidney stones, cardiac arrhythmias).