Elevated Creatine Kinase

Carnosine supplementation may cause a slight increase in creatine kinase (CK) levels, potentially concerning for individuals with pre-existing kidney problems or other risk factors. Elevated CK indicates muscle damage and, if significantly high, can lead to complications.

Elevated creatine kinase (CK) levels indicate muscle damage or stress. Carnosine supplementation may cause a slight increase in CK in some individuals. This elevation is often asymptomatic but can be a concern because significantly elevated CK levels can, in rare cases, indicate rhabdomyolysis, a serious condition where damaged muscle tissue releases proteins and electrolytes into the blood, potentially leading to kidney damage or failure, cardiac arrhythmia, or even death. While carnosine-induced CK elevation is typically not that severe, it warrants caution, particularly for individuals with pre-existing kidney conditions, neuromuscular disorders, or those taking medications known to affect CK levels.