Thiamine (Vitamin B1) is an essential water-soluble vitamin crucial for energy metabolism, nerve function, cognitive health, and heart health. It functions as a coenzyme in carbohydrate metabolism, fa...
Thiamine (Vitamin B1) is an essential water-soluble vitamin crucial for energy metabolism, nerve function, cognitive health, and heart health. It functions as a coenzyme in carbohydrate metabolism, facilitating the conversion of glucose into energy and supporting neurotransmitter synthesis. While found in natural sources, it is also synthesized for supplementation and food fortification. Deficiency can result in serious health issues like beriberi and Wernicke-Korsakoff syndrome. Supplementation is generally safe, with mild side effects reported in rare cases at high doses. Adequate intake is vital for overall well-being, particularly for individuals at risk of deficiency due to dietary restrictions, alcoholism, or certain medical conditions.
Key Information
Inside Body Harmful Score
Common Dosage
1-2mg daily (RDA); 5-100mg daily (supplemental)
Source Type
hybrid
Production Process
Thiamine is obtained from natural sources like whole grains, legumes, and meat. It is also produced synthetically through chemical synthesis, typically involving condensation and cyclization reactions.
Use Type
Inside BodyPotential Benefits
Enhances mental processes involved in thinking, learning, and remembering, including memory, attention, focus, and processing speed. Benefits range from improved mental clarity to significant enhancements in cognitive abilities, especially in those with cognitive decline.
Supports healthy nerve function in both the central and peripheral nervous systems. This includes nerve signal transmission, nerve cell protection, and nerve regeneration.
This benefit supports cardiovascular function by maintaining healthy blood pressure, cholesterol, and blood vessel elasticity, ultimately reducing the risk of heart disease. It also manages inflammation for overall heart health.
Cardiovascular health ensures efficient blood circulation by maintaining healthy heart and blood vessels. Benefits include reduced risk of heart disease and stroke through improved blood flow and heart function.
Energy metabolism is the process of converting nutrients into energy (ATP), essential for bodily functions. Efficient energy metabolism supports physical activity, reduces fatigue, and contributes to overall health, while dysfunction can lead to metabolic disorders.
Supports nerve health and function in both the peripheral and central nervous systems by promoting regeneration, reducing pain and inflammation, improving signal transmission, and protecting against damage. This contributes to optimal sensory perception, motor control, and neurological function.
Possible Side Effects
Gastrointestinal upset involves a variety of digestive symptoms like nausea, diarrhea, and abdominal pain. It can range from mild discomfort to severe pain and may indicate an underlying condition if persistent.
Hypothetically, this substance can cause mild skin irritation with redness, itching, and burning at the application site, resolving on its own.
Allergic reactions are hypersensitivity responses to allergens, ranging from mild skin irritation to life-threatening anaphylaxis. Symptoms vary widely and are caused by an immune response.
Scientific Evidence
PubMed: [Search terms: 'thiamine metabolism', 'thiamine deficiency symptoms', 'thiamine nerve function', 'thiamine cognitive function', 'thiamine heart failure']; NIH Office of Dietary Supplements: [Vitamin B1 Fact Sheet]
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