Tetrahydrocurcuminoids

Outside Body
Outside: Harmless

Tetrahydrocurcuminoids (THC) are a group of hydrogenated derivatives of curcuminoids derived from turmeric. They are considered to be more bioavailable and stable than their parent curcuminoids. THC e...

Tetrahydrocurcuminoids (THC) are a group of hydrogenated derivatives of curcuminoids derived from turmeric. They are considered to be more bioavailable and stable than their parent curcuminoids. THC exhibits antioxidant and anti-inflammatory properties, offering potential benefits for overall health, including skin health, cardiovascular health, and joint support. While generally safe, gastrointestinal distress and allergic reactions are possible, especially at high doses.

Key Information

Outside Body Harmful Score

Harmless

Common Dosage

100-250mg daily

Source Type

natural

Production Process

Tetrahydrocurcuminoids (THC) are produced by hydrogenating curcuminoids extracted from turmeric (Curcuma longa) rhizomes. This process involves using catalysts to add hydrogen atoms to the unsaturated bonds in curcumin, demethoxycurcumin, and bisdemethoxycurcumin, resulting in their respective tetrahydro derivatives. The resulting mixture is then typically purified and standardized for THC content.

Use Type

Outside Body

Potential Benefits

This benefit aims to improve overall skin health and appearance through increased hydration, reduced inflammation, improved elasticity, and protection from environmental damage. Healthy skin exhibits a smooth texture, even tone, and strong barrier function.

2/5

Cardiovascular health ensures efficient blood circulation by maintaining healthy heart and blood vessels. Benefits include reduced risk of heart disease and stroke through improved blood flow and heart function.

2/5

Reduces inflammation by inhibiting inflammatory pathways and the production of inflammatory molecules, thereby alleviating symptoms and protecting against tissue damage. This benefit helps modulate inflammatory responses and promote resolution.

3/5

Aged garlic extract acts as an antioxidant by neutralizing free radicals, protecting cells from damage and potentially reducing the risk of chronic diseases. The allicin-derived metabolites are the active components.

4/5

Possible Side Effects

Allergic Reactions

Allergic reactions are hypersensitivity responses to allergens, ranging from mild skin irritation to life-threatening anaphylaxis. Symptoms vary widely and are caused by an immune response.

medium
Gastrointestinal Distress

Gastrointestinal distress involves digestive discomfort like bloating, diarrhea, cramps, nausea, and vomiting. Severity varies based on individual factors and can be triggered by irritation or inflammation of the digestive tract.

low

Scientific Evidence

Menon VP, Sudheer AR. Antioxidant and anti-inflammatory properties of curcumin. Adv Exp Med Biol. 2007;595:105-25.; Khajehdehi P, Pakfetrat M, Javidnia K, et al. Oral supplementation of turmeric attenuates proteinuria, transforming growth factor-β and interleukin-8 levels in patients with overt type 2 diabetic nephropathy: a randomized, double-blind and placebo-controlled study. J Ren Nutr. 2011;21(5):481-489.; Wongcharoen W, Phrommintikul A. The protective role of curcumin in cardiovascular diseases. Int J Cardiol. 2009;133(2):145-151.

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