Quercetin is a naturally occurring flavonoid found in various fruits and vegetables, known for its antioxidant and anti-inflammatory properties. Supplementation may offer benefits for immune function,...
Quercetin is a naturally occurring flavonoid found in various fruits and vegetables, known for its antioxidant and anti-inflammatory properties. Supplementation may offer benefits for immune function, cardiovascular health, and allergy relief. Its primary mechanisms of action involve reducing oxidative stress and inflammation. While generally considered safe at recommended doses, potential side effects like headache and upset stomach can occur. Drug interactions, particularly with blood thinners, should be carefully considered. Ongoing research is aimed at further understanding the potential therapeutic applications of quercetin.
Key Information
Inside Body Harmful Score
Common Dosage
500-1000mg daily, often divided into multiple doses
Source Type
natural
Production Process
Extracted from various plant sources, including fruits and vegetables, often onion skins and apple peels. Can also be produced synthetically, although natural extraction is more common for dietary supplements.
Use Type
Inside BodyPotential Benefits
This benefit focuses on decreasing inflammation throughout the body by lowering inflammatory markers, alleviating symptoms of chronic inflammation, and promoting healthy tissue and organ function. It aims to reduce pain, improve movement, and lower the chances of developing long-term diseases related to inflammation.
Antioxidant support protects cells from damage by neutralizing free radicals, supporting immune function, and reducing inflammation. It contributes to overall health and may reduce the risk of chronic diseases.
Immune support enhances the body's defense against pathogens by strengthening immune cells, promoting antibody production, and maintaining immune homeostasis. It aims to optimize immune function for a balanced and resilient response to threats.
Cardiovascular health ensures efficient blood circulation by maintaining healthy heart and blood vessels. Benefits include reduced risk of heart disease and stroke through improved blood flow and heart function.
Reduces allergy symptoms like sneezing, runny nose, and skin rashes through antihistamine, anti-inflammatory, or immune-modulating effects. Suitability varies based on the allergy and individual response.
Antioxidant protection defends the body against free radical damage, reducing the risk of chronic diseases and promoting overall cellular health. This is achieved by neutralizing unstable molecules that cause oxidative stress and cellular damage.
Reduces inflammation by inhibiting inflammatory pathways and the production of inflammatory molecules, thereby alleviating symptoms and protecting against tissue damage. This benefit helps modulate inflammatory responses and promote resolution.
Reishi mushrooms contain triterpenes that may reduce inflammation by modulating inflammatory pathways. This could benefit conditions associated with chronic inflammation.
Quercetin modulates immune cells to enhance immune function and reduce infection risk. It may also inhibit viral entry and replication.
Possible Side Effects
Headache is pain in the head ranging from mild to severe, potentially with nausea, light/sound sensitivity, or dizziness. It can be caused by tension, dehydration, stress, or medication side effects, and persistent headaches require medical evaluation.
Upset stomach, or dyspepsia, involves upper abdominal discomfort with symptoms like nausea, bloating, and heartburn. It can stem from various factors and may require investigation if persistent.
Drug interactions can alter a drug's effectiveness, leading to either increased risk of blood clots or bleeding, particularly with anticoagulants. Monitoring is essential to manage these interactions.
Kidney damage is a theoretical side effect associated with very high doses, particularly intravenous, of the substance. Evidence is limited, requiring further human research to confirm the risk and potential symptoms.
Scientific Evidence
Several studies have investigated the effects of quercetin on various health conditions. Examples include: (1) Studies on quercetin's impact on immune cell activity and cytokine production (e.g., specific references to research on quercetin's effects on T cells and macrophages). (2) Research on quercetin's effects on blood pressure, endothelial function, and cholesterol levels (e.g., meta-analyses of clinical trials). (3) Studies on quercetin's ability to stabilize mast cells and reduce histamine release in allergic reactions. (4) Studies demonstrating quercetin's ability to scavenge free radicals and protect against oxidative damage in vitro and in vivo (e.g. research focusing on Nrf2 activation). Further search on PubMed or Google Scholar for specific studies is encouraged.
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