Milk Thistle (Silymarin)

Inside Body
Inside: Harmless
0.0

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Milk thistle, specifically the silymarin complex extracted from its seeds, is a widely used herbal supplement recognized for its potential liver-protecting, antioxidant, and anti-inflammatory properti...

Milk thistle, specifically the silymarin complex extracted from its seeds, is a widely used herbal supplement recognized for its potential liver-protecting, antioxidant, and anti-inflammatory properties. Research suggests it may offer benefits for liver health, blood sugar management, and cholesterol reduction. While generally considered safe, mild gastrointestinal discomfort and allergic reactions are possible. Further high-quality research is needed to fully understand and confirm these effects.

Key Information

Inside Body Harmful Score

Harmless

Common Dosage

200-600mg daily, divided into 2-3 doses

Source Type

natural

Production Process

Silymarin is extracted from the seeds of the milk thistle plant (Silybum marianum) through various solvent extraction methods. The extract is then often standardized to a specific percentage of silymarin flavonoids.

Use Type

Inside Body

Potential Benefits

This benefit supports liver function by promoting detoxification, cell regeneration, and reducing inflammation. A healthy liver is essential for various metabolic processes and overall well-being.

4/5

This benefit lowers total, LDL cholesterol, and triglycerides while potentially raising HDL cholesterol, promoting cardiovascular health. It achieves this through multiple mechanisms affecting absorption, excretion, and synthesis of cholesterol.

2/5

Blood sugar control maintains blood glucose levels within a healthy range, preventing hyperglycemia and hypoglycemia. This involves insulin regulation, glucose uptake, and liver glucose production, crucial for preventing conditions like type 2 diabetes.

3/5

Detoxification describes the body's natural process of eliminating toxins via organs like the liver and kidneys. Commercial 'detox' products claim to support these processes, but evidence is often limited.

3/5

Aged garlic extract acts as an antioxidant by neutralizing free radicals, protecting cells from damage and potentially reducing the risk of chronic diseases. The allicin-derived metabolites are the active components.

3/5

Silymarin protects the liver from damage caused by toxins and promotes liver cell regeneration through its antioxidant and anti-inflammatory properties. It supports liver function by neutralizing harmful substances and aiding in repair.

4/5

Possible Side Effects

Gastrointestinal Upset

Gastrointestinal upset involves a variety of digestive symptoms like nausea, diarrhea, and abdominal pain. It can range from mild discomfort to severe pain and may indicate an underlying condition if persistent.

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Headache

Headache is pain in the head ranging from mild to severe, potentially with nausea, light/sound sensitivity, or dizziness. It can be caused by tension, dehydration, stress, or medication side effects, and persistent headaches require medical evaluation.

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Laxative Effect

A laxative effect is an increase in bowel movements, often leading to loose or frequent stools, due to various substances stimulating bowel motility or altering water absorption/secretion in the intestines. Unintended laxative effects can cause dehydration and electrolyte imbalance.

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Allergic Reactions

Allergic reactions are hypersensitivity responses to allergens, ranging from mild skin irritation to life-threatening anaphylaxis. Symptoms vary widely and are caused by an immune response.

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Scientific Evidence

Several clinical trials and meta-analyses have examined the effects of silymarin on liver health, blood sugar, and cholesterol. Key studies include those published in journals such as the American Journal of Gastroenterology, the World Journal of Gastroenterology, and Phytotherapy Research. Search PubMed and Google Scholar for 'silymarin' and relevant conditions for further details.

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