Gluconolactone (PHA) gently exfoliates, hydrates, and provides antioxidant benefits in skincare, also used as a food additive.
Gluconolactone (PHA) is a polyhydroxy acid derived from glucose oxidation, widely used in skincare for its gentle exfoliating, hydrating, and antioxidant effects. It's considered a suitable alternative to AHAs, especially for sensitive skin. While generally safe, mild skin irritation and increased sun sensitivity are potential side effects. It is also used as a food additive functioning as a sequestrant, acidulant and leavening agent. Oral consumption dosages for specific health benefits are not well-defined, but topical application is common in varying concentrations depending on the product formulation.
Key Information
Outside Body Harmful Score
Common Dosage
Oral consumption dosages are not well-established for specific health benefits. In skincare, concentrations vary widely in formulations (e.g., 1-20%).
Source Type
synthetic
Production Process
Gluconolactone is produced through the oxidation of glucose, often using fermentation processes.
Use Type
Outside BodyPotential Benefits
Hydration ensures sufficient body water for optimal function, supporting processes like temperature regulation and nutrient transport. It prevents dehydration and associated symptoms like fatigue and cognitive impairment.
Exfoliation removes dead skin cells to improve skin texture, tone, and radiance. It also unclogs pores, prevents acne, and boosts collagen production.
Antioxidants neutralize harmful free radicals, preventing cellular damage and reducing oxidative stress, which can contribute to overall health and disease prevention. They work by donating electrons to stabilize free radicals and supporting antioxidant enzyme systems.
Gluconolactone is a humectant that attracts and binds water to the skin, providing hydration. It also acts as a mild exfoliant for smoother skin texture.
PHAs strengthen the skin barrier by promoting ceramide synthesis. This enhances skin hydration and protection against external irritants.
Possible Side Effects
Skin irritation involves symptoms like redness, itching, and rashes due to contact with irritants, allergens, or environmental factors. Severity varies based on the cause, individual sensitivity, and affected area; persistent cases may lead to secondary infections.
Sun sensitivity is an increased susceptibility to UV radiation, leading to exaggerated sunburn reactions and potential long-term skin damage. It can be triggered by medications, medical conditions, or topical products.
Scientific Evidence
Studies on gluconolactone's use in skincare, including its efficacy in exfoliation, hydration, and antioxidant protection, as well as its lower irritancy compared to AHAs. Research on its role as a food additive. Further clinical trials are needed to establish the effects of oral consumption.
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