Fullerenes (C60) are synthetic carbon molecules attracting research interest for their antioxidant, neuroprotective, and anti-inflammatory properties. Studies, primarily in animal models, have shown p...
Fullerenes (C60) are synthetic carbon molecules attracting research interest for their antioxidant, neuroprotective, and anti-inflammatory properties. Studies, primarily in animal models, have shown potential benefits such as lifespan extension. However, significant concerns exist regarding safety, bioavailability, and formulation-dependent toxicity. The lack of human clinical trials and comprehensive safety data necessitates caution in their use. Further research is crucial to determine their suitability for human consumption.
Key Information
Outside Body Harmful Score
Common Dosage
No established safe or effective human dosage. Dosages used in animal studies vary widely and are not directly translatable to humans.
Source Type
synthetic
Production Process
Typically produced through vaporizing graphite using arc discharge or laser ablation techniques in an inert atmosphere. The resulting soot is then processed to isolate and purify the C60 fullerenes.
Use Type
Outside BodyPotential Benefits
Ferulic acid may protect brain cells from damage and cognitive decline due to its antioxidant and anti-inflammatory properties. More research is needed to confirm these potential neuroprotective benefits.
C60 neutralizes free radicals, reducing oxidative stress and promoting cellular health due to its unique structure and ability to accept multiple free radicals. This antioxidant activity can help protect against cellular damage.
C60 exhibits anti-inflammatory properties by scavenging free radicals and reducing oxidative stress. This can potentially alleviate inflammatory conditions.
C60 (dissolved in olive oil) has extended lifespan in rodent studies, likely due to antioxidant and anti-inflammatory effects. The human applicability and detailed mechanisms are still under investigation.
Panthenol exhibits anti-inflammatory properties by stabilizing skin barrier function and potentially reducing pro-inflammatory cytokine production. This results in soothing and calming irritated or inflamed skin.
Possible Side Effects
Topical application can cause skin irritation, manifesting as redness, itching, and other symptoms. Severity varies based on individual factors and exposure, usually resolving after stopping use.
C60 toxicity depends on formulation, concentration, and administration route. Potential effects include liver toxicity, immune system alterations, and organ accumulation, especially with poorly soluble forms.
The long-term effects of C60 on humans are not well-understood due to a lack of research, raising concerns about potential, as yet unidentified, health issues arising from prolonged exposure.
Scientific Evidence
Key scientific sources and studies include research on fullerene antioxidant mechanisms (e.g., EPR spectroscopy studies), neuroprotective effects in animal models of Parkinson's disease, and toxicity assessments in various cell lines and animal species. Search for studies involving 'C60 fullerene toxicity', 'C60 antioxidant activity', and 'C60 neuroprotection' on PubMed and similar databases.
User Reviews
Share your experience with this ingredient
Log in to write a reviewNo reviews yet. Be the first to share your experience!