FD&C Red No. 40 is a synthetic azo dye derived from petroleum, widely used as a color additive in food products and supplements. Its primary function is to improve visual appeal. While it offers no nu...
FD&C Red No. 40 is a synthetic azo dye derived from petroleum, widely used as a color additive in food products and supplements. Its primary function is to improve visual appeal. While it offers no nutritional benefits, concerns exist regarding its potential link to hyperactivity, especially in children, and allergic reactions in sensitive individuals. The scientific community continues to debate the strength of the association between FD&C Red No. 40 and hyperactivity. Individuals with concerns may choose to avoid products containing this dye.
Key Information
Inside Body Harmful Score
Common Dosage
Not applicable; FD&C Red #40 is a color additive, not a nutrient or active ingredient, therefore dosage is not typically considered.
Source Type
synthetic
Production Process
FD&C Red No. 40 is synthesized from petroleum. Specifically, it is an azo dye created through diazotization of 5-amino-4-methoxy-2-sulfonic acid, followed by coupling with naphthol-6-sulfonic acid.
Use Type
Inside BodyPotential Benefits
Possible Side Effects
Allergic reactions are hypersensitivity responses to allergens, ranging from mild skin irritation to life-threatening anaphylaxis. Symptoms vary widely and are caused by an immune response.
Hyperactivity involves excessive activity, restlessness, and difficulty concentrating. It can be a side effect of medications or substances and may disrupt daily activities.
ADHD Symptoms encompass inattentiveness, hyperactivity, and impulsivity caused by substance or treatment interactions with neurotransmitters or brain regions. Severity varies widely, influenced by pre-existing conditions and concurrent medications.
Behavioral issues involve changes in conduct and emotional regulation, potentially manifesting as irritability, anxiety, or social withdrawal. These changes vary based on the cause and individual factors, requiring careful evaluation of context and impact.
Behavioral problems include aggression, irritability, and mood swings, primarily affecting children. These symptoms can disrupt daily life and may require intervention.
Scientific Evidence
McCann D, Barrett A, Cooper A, et al. Food additives and hyperactive behaviour in 3-year-old and 8/9-year-old children in the community: a randomised, double-blinded, placebo-controlled trial. Lancet. 2007 Nov 3;370(9598):1560-7.
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