Diosmin is a flavonoid glycoside primarily found in citrus fruits. It is commonly used as a dietary supplement to support vascular health, particularly in the treatment of chronic venous insufficiency...
Diosmin is a flavonoid glycoside primarily found in citrus fruits. It is commonly used as a dietary supplement to support vascular health, particularly in the treatment of chronic venous insufficiency and hemorrhoids. It is believed to improve venous tone, reduce capillary permeability, and possess anti-inflammatory properties. While generally well-tolerated, potential side effects include mild gastrointestinal disturbances and headaches.
Key Information
Inside Body Harmful Score
Common Dosage
450-900mg daily, typically divided into multiple doses.
Source Type
natural
Production Process
Diosmin is typically derived from citrus fruits, particularly bitter oranges. It is often extracted from hesperidin, another flavonoid, and then converted into diosmin through a chemical process.
Use Type
Inside BodyPotential Benefits
Hesperidin and diosmin combination helps alleviate venous insufficiency symptoms like leg pain, swelling, and heaviness by strengthening blood vessel walls and improving blood flow.
Diosmin aims to relieve CVI symptoms by enhancing venous tone and reducing capillary permeability, improving blood flow and alleviating leg pain, swelling, heaviness, and cramps. It targets the vascular system to promote better circulation in the veins.
Diosmin and hesperidin are used to treat acute hemorrhoidal attacks. They reduce pain, bleeding, and swelling by improving venous tone and reducing inflammation.
Diosmin may aid in lymphedema management by reducing swelling and improving lymphatic drainage, potentially through strengthening blood vessels and reducing inflammation. It aims to improve lymphatic system efficiency to decrease fluid accumulation.
Diosmin, especially when combined with hesperidin, can help heal venous leg ulcers by improving blood flow and reducing inflammation in the affected area. This aids in tissue repair and reduces swelling and discomfort.
Possible Side Effects
Dizziness is a sensation of lightheadedness, unsteadiness, or vertigo that can arise from multiple causes. It can lead to falls or loss of consciousness in some cases.
Headache is pain in the head ranging from mild to severe, potentially with nausea, light/sound sensitivity, or dizziness. It can be caused by tension, dehydration, stress, or medication side effects, and persistent headaches require medical evaluation.
Mild gastrointestinal disturbances, including nausea, abdominal pain, diarrhea, and dyspepsia, can occur. These symptoms are generally not severe and may resolve on their own.
Scientific Evidence
Several clinical trials have demonstrated the efficacy of diosmin, often in combination with hesperidin, in improving symptoms of CVI and hemorrhoids. Key studies include those published in the International Angiology journal and the Phlebology journal. Further research is ongoing to explore its potential benefits in other vascular conditions and lymphedema.
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