Calendula extract is a natural remedy derived from the Calendula officinalis flower, widely used for its potential wound-healing, anti-inflammatory, and antimicrobial properties. It is commonly applie...
Calendula extract is a natural remedy derived from the Calendula officinalis flower, widely used for its potential wound-healing, anti-inflammatory, and antimicrobial properties. It is commonly applied topically in creams, ointments, and lotions to treat skin conditions, wounds, and burns. While generally considered safe, allergic reactions and photosensitivity are possible. Oral consumption is less common and should be done under the guidance of a healthcare professional. Research is ongoing to further understand the mechanisms and efficacy of calendula extract.
Key Information
Outside Body Harmful Score
Common Dosage
Varies widely depending on the specific product and intended use. Creams and ointments typically contain 2-10% calendula extract. For oral consumption, doses range from 300-900mg daily in divided doses, but consult with a healthcare professional for personalized recommendations.
Source Type
natural
Production Process
Calendula extract is typically produced by macerating or extracting the flower heads of the Calendula officinalis plant in a solvent, such as water, ethanol, or glycerin. The solvent is then filtered, and the extract is often concentrated or standardized to specific active compounds.
Use Type
Outside BodyPotential Benefits
Skin hydration is essential for maintaining skin elasticity, barrier function, and overall appearance. It reduces fine lines, protects against environmental stressors, and improves skin smoothness and suppleness.
Accelerates and supports the body's natural wound repair processes. This includes reducing inflammation, promoting collagen synthesis, increasing cell proliferation, and facilitating angiogenesis, leading to faster wound closure, reduced scarring, and decreased infection risk.
This benefit reduces inflammation by modulating inflammatory pathways and inhibiting pro-inflammatory cytokines, resulting in reduced pain, swelling, and improved function. It is beneficial for conditions like arthritis, inflammatory bowel disease, cardiovascular disease, and skin conditions.
Bisabolol has antimicrobial effects against some bacteria and fungi, contributing to skin protection. It disrupts cell membranes and inhibits microbial growth.
Possible Side Effects
Allergic reactions are hypersensitivity responses to allergens, ranging from mild skin irritation to life-threatening anaphylaxis. Symptoms vary widely and are caused by an immune response.
Photosensitivity is an increased sensitivity to UV radiation, leading to sunburn, rash, or blistering. Reactions can be phototoxic or photoallergic, with symptoms ranging from mild redness to severe blistering and potentially increasing skin cancer risk with prolonged exposure.
Calendula may have sedative effects, potentially enhancing the effects of other sedatives. Use with caution when combined with other sedative medications.
Scientific Evidence
Several studies suggest benefits for wound healing and anti-inflammatory effects. A randomized controlled trial published in the Journal of Wound Care (2001) showed that calendula ointment significantly accelerated the healing of venous leg ulcers. Another study in the Journal of Clinical Nursing (2016) demonstrated its effectiveness in preventing radiation dermatitis in breast cancer patients. Preliminary research also supports its antimicrobial activity. More robust, large-scale clinical trials are needed to confirm and expand upon these findings.
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