Asiaticoside promotes wound healing, collagen synthesis, and reduces inflammation in skincare and wound care.
Asiaticoside is a triterpenoid glycoside extracted from Centella asiatica, renowned for its wound-healing, anti-inflammatory, and scar-reducing properties. It promotes collagen synthesis and angiogenesis. Topical application may occasionally lead to mild skin irritation, while oral consumption might cause minor gastrointestinal issues. Its potential anti-aging effects are also being explored. Dosages vary depending on whether it is applied topically or ingested orally.
Key Information
Outside Body Harmful Score
Common Dosage
Dosage varies depending on the application method. Topical applications usually involve creams or ointments containing 0.1-1% Asiaticoside. Oral dosages in supplements range from 60-600mg daily, divided into multiple doses.
Source Type
natural
Production Process
Asiaticoside is extracted from the Centella asiatica plant using various solvent extraction methods, followed by purification and isolation techniques to obtain the compound.
Use Type
Outside BodyPotential Benefits
Anti-aging interventions protect cells from damage, promote cellular repair, and reduce the risk of age-related diseases. Strategies include dietary interventions, supplementation, lifestyle modifications, and topical treatments to improve overall health and well-being.
Accelerates and supports the body's natural wound repair processes. This includes reducing inflammation, promoting collagen synthesis, increasing cell proliferation, and facilitating angiogenesis, leading to faster wound closure, reduced scarring, and decreased infection risk.
This benefit reduces inflammation by modulating inflammatory pathways and inhibiting pro-inflammatory cytokines, resulting in reduced pain, swelling, and improved function. It is beneficial for conditions like arthritis, inflammatory bowel disease, cardiovascular disease, and skin conditions.
Bakuchiol stimulates collagen production, improving skin elasticity and reducing the appearance of fine lines and wrinkles. It enhances skin tone and texture for a more youthful appearance.
Rosehip oil may reduce the appearance of scars, including surgical and acne scars, by promoting skin regeneration and reducing inflammation and discoloration. Its fatty acids and antioxidants aid in the healing process and improve skin texture.
Possible Side Effects
Gastrointestinal upset involves a variety of digestive symptoms like nausea, diarrhea, and abdominal pain. It can range from mild discomfort to severe pain and may indicate an underlying condition if persistent.
Skin irritation involves symptoms like redness, itching, and rashes due to contact with irritants, allergens, or environmental factors. Severity varies based on the cause, individual sensitivity, and affected area; persistent cases may lead to secondary infections.
Gastrointestinal issues include nausea, diarrhea, abdominal discomfort, and vomiting, potentially stemming from altered gut motility, microbiota changes, or irritation. While often mild, persistent symptoms necessitate evaluation, and contributing factors like pre-existing conditions should be considered.
Scientific Evidence
Several in vitro and in vivo studies support the wound-healing and anti-inflammatory properties of asiaticoside. Clinical trials have demonstrated its efficacy in improving scar appearance and accelerating wound closure. Further research is ongoing to fully elucidate its mechanisms of action and potential therapeutic applications. Examples include studies published in the Journal of Ethnopharmacology and the International Journal of Molecular Sciences.
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