Allantoin soothes, moisturizes, and heals skin by promoting renewal and hydration.
Allantoin is a synthetically produced ingredient widely used in skincare for its skin-soothing, moisturizing, and wound-healing properties. Functioning as both a humectant and keratolytic agent, it promotes healthy skin renewal and hydration, improving skin texture and reducing irritation. It is generally well-tolerated in topical applications, with infrequent reports of minor skin irritation or allergic reactions. Its ability to stimulate cell proliferation and epithelization supports its role in wound healing.
Key Information
Outside Body Harmful Score
Common Dosage
Concentrations in topical formulations typically range from 0.5% to 2%.
Source Type
synthetic
Production Process
Synthesized from urea and glyoxylic acid, or by oxidation of uric acid.
Use Type
Outside BodyPotential Benefits
Accelerates and supports the body's natural wound repair processes. This includes reducing inflammation, promoting collagen synthesis, increasing cell proliferation, and facilitating angiogenesis, leading to faster wound closure, reduced scarring, and decreased infection risk.
Skin soothing alleviates irritation and inflammation by reducing inflammatory responses, protecting the skin, and hydrating it. It provides relief from redness, itching, dryness and pain, improving skin comfort and barrier repair.
Allantoin hydrates the skin by drawing in moisture and preventing water loss, leading to increased skin suppleness and reduced dryness.
Allantoin exhibits a keratolytic effect, encouraging the shedding of dead skin cells and improving skin texture. This process may reduce the appearance of scars and promote healthy skin renewal.
Possible Side Effects
Skin irritation involves symptoms like redness, itching, and rashes due to contact with irritants, allergens, or environmental factors. Severity varies based on the cause, individual sensitivity, and affected area; persistent cases may lead to secondary infections.
Allergic reactions are adverse immune responses to normally harmless substances, ranging from mild skin irritation to severe anaphylaxis. Symptoms can include skin issues, swelling, breathing difficulties, and anaphylaxis requires immediate epinephrine injection.
Scientific Evidence
Becker, L. C., Bergfeld, W. F., Belsito, D. V., Klaassen, C. D., Marks, J. G., Shank, R. C., ... & Andersen, F. A. (2010). Final report on the safety assessment of allantoin and its related complexes. International journal of toxicology, 29(3 Suppl), 84S-93S. / Araujo, L. U., Campos, P. M. B. G. M., & Gaspar, L. R. (2010). Development and stability study of emulsion containing allantoin. Brazilian Journal of Pharmaceutical Sciences, 46(1), 135-142.
User Reviews
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